The data graphs below compare isolated cannabidiol ( CBD) against a full-spectrum cannabis extract (from a CBD-rich strain). The results clearly show the medical benefit of extracting all the different compounds from the entirety of the raw cannabis flower, rather than extraction of a single cannabinoid.Ĭannabis Testing on Mice (AP Photo/Robert F. The study was represented by 10-12 mice per treatment group, using known laboratory methods for measuring reductions in inflammation and pain sensation (described at length in the study). In addition to a control group, the commercial drugs aspirin and tramadol were used on separate sets of mice to further compare the effectiveness of synthetic isolations versus whole plant extracts. The tests were performed on ethically-approved lab mice from Hadassah Medical School. The pure CBD extract and the full-spectrum extract were formulated for both injection and oral administration. Bred to be rich in CBD, the raw flowers of this whole plant extract were ground up and cannabinoids were extracted using the solvent ethanol. For the whole plant extract, flowers from the clone 202 (proprietary strain: Avidekel) were supplied by the government-approved growers Tikun Olam Company. GmbH (Frankfurt, Germany) to act as the pharmaceutical grade isolated extract.
The purified CBD was acquired from THC Pharm.
Materials Used: Plants, Animals, and Extracts When supplied as an isolated cannabinoid extract, CBD on its own yielded a bell-curve of effectiveness, which is not desirable for medical treatments seeking effective relief that corresponds with the dosage. The study demonstrated that a whole plant extract, containing the entire range of cannabinoids present in raw cannabis, will continue to provide relief for inflammation as the dose is increased. The conclusion of the study was that the whole plant extract, which contained a large percentage of CBD but also contained traces of the other cannabinoids, proved far more effective than CBD-only solutions in alleviating inflammation and pain sensation. The Hadassah Medical School at the Hebrew University of Jerusalem sought to compare the effectiveness of a completely purified CBD extract versus a full-spectrum extract of cannabis flowers containing large quantities of CBD. Cannabis Testing at The Hebrew University of Jerusalem, Israel ( source)
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